Are you taking all your asthma medicines* but still struggling with:

Poor symptom control
Such as coughing, wheezing, difficulty breathing, frequent use of a rescue inhaler and waking up at night
Worsening asthma
A flare-up of your asthma, also called exacerbations or severe asthma attacks, when symptoms don't improve and you need to add oral steroids
ER visits or hospitalizations
Due to the severity of your
asthma attacks
If yes, your asthma is most likely severe and eosinophils may be the reason why.

*Asthma controller medicines, including high-dose inhaled corticosteroid.

What are eosinophils?

Eosinophils [ee-uh-sin-uh-fils] are normal white blood cells in your body. You may have increased levels of eosinophils, which can worsen inflammation in your lungs. Inflammation can cause severe asthma attacks.

Your doctor can give you a test that measures eosinophils in your blood to help determine if your asthma is an eosinophilic type. Together, you will decide if adding a different kind of asthma treatment could help.

Ask your doctor for a simple blood test to see if you should add NUCALA, a treatment designed to target eosinophils.

NUCALA can prevent severe asthma attacks and reduce the use of oral steroids while maintaining asthma control.

Did you know?

Repeated asthma attacks and inflammation caused by long-term, uncontrolled asthma can lead to more asthma attacks, or exacerbations.

What to do now

Most severe asthma can be controlled. Tell your doctor about everything you're doing to manage your asthma.

  1. Tell your doctor when your symptoms get worse
  2. Tell your doctor when asthma interferes with your daily activities
  3. Ask for a blood test to see if your asthma is the eosinophilic type
  4. Ask your doctor if NUCALA may be right for you

Telling your doctor about all your symptoms and how they affect your life will lead to the best treatment for your severe asthma.

Questions?

Get more information about severe asthma and NUCALA.

See FAQs

Find an asthma specialist, such as an allergist or pulmonologist, who may help

Find a doctor

What can NUCALA do for you?

Learn about NUCALA

Talk to your doctor to see if adding NUCALA for your severe asthma is right for you.

Approved Uses

NUCALA is an add-on, prescription maintenance treatment for patients 12 and older with severe eosinophilic asthma. NUCALA is not used to treat sudden breathing problems.

Important Safety Information

Do not use NUCALA if you are allergic to mepolizumab or any of the ingredients in NUCALA.

Approved Use

NUCALA is an add-on, prescription maintenance treatment for patients 12 and older with severe eosinophilic asthma. NUCALA is not used to treat sudden breathing problems.

Important Safety Information

Do not use NUCALA if you are allergic to mepolizumab or any of the ingredients in NUCALA.

Do not use to treat sudden breathing problems.

NUCALA can cause serious side effects, including:

  • allergic (hypersensitivity) reactions, including anaphylaxis. Serious allergic reactions can happen after you get your injection of NUCALA. Allergic reactions can sometimes happen hours or days after you get a dose of NUCALA. Tell your healthcare provider or get emergency help right away if you have any of the following symptoms of an allergic reaction:
    • swelling of your face, mouth, and tongue
    • breathing problems
    • fainting, dizziness, feeling light-headed (low blood pressure)
    • rash
    • hives
  • Herpes zoster infections that can cause shingles have happened in people who received NUCALA.

Before receiving NUCALA, tell your healthcare provider about all of your medical conditions, including if you:

  • are taking oral or inhaled corticosteroid medicines. Do not stop taking your other asthma medicines, including your corticosteroid medicines, unless instructed by your healthcare provider because this may cause other symptoms to come back.
  • have a parasitic (helminth) infection.
  • are pregnant or plan to become pregnant. It is not known if NUCALA may harm your unborn baby.
    • A pregnancy registry for women who receive NUCALA while pregnant collects information about the health of you and your baby. You can talk to your healthcare provider about how to take part in this registry or you can get more information and register by calling 1-877-311-8972 or visit www.mothertobaby.org/asthma.
  • are breastfeeding or plan to breastfeed. You and your healthcare provider should decide if you will use NUCALA and breastfeed. You should not do both without talking with your healthcare provider first.
  • are taking prescription and over-the-counter medicines, vitamins, and herbal supplements.

The most common side effects of NUCALA include: headache, injection site reactions (pain, redness, swelling, itching, or a burning feeling at the injection site), back pain, and weakness (fatigue).

You are encouraged to report negative side effects of prescription drugs to the FDA.Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.