How does NUCALA work?

NUCALA targets eosinophils, but what exactly does that mean?

What are eosinophils?

Eosinophils [ee-uh-sin-uh-fils] are white blood cells that are a normal part of the body’s immune system.

How do eosinophils play a role in severe asthma?

Too many eosinophils may lead to inflammation in your lungs. Inflammation can cause severe asthma attacks.

NUCALA reduces eosinophils

NUCALA is not a steroid like prednisone. It is designed to reduce the number of eosinophils in your blood.

The mechanism of action of NUCALA is not fully understood.

Reducing the number of eosinophils in your blood may help reduce airway inflammation

NUCALA helps you gain asthma control and helps reduce your use of oral steroids like prednisone. It’s important to receive your injection of NUCALA once every four weeks as prescribed, even if you’re feeling better.

Blood Test

A simple blood test can measure the number of eosinophils in your blood

In clinical studies, this helped identify patients whose asthma was more likely to respond to treatment with NUCALA.

Based on your test results, your doctor may add NUCALA to your treatment.


See how NUCALA targets eosinophils to help reduce airway inflammation*



See what NUCALA can do.