Frequently Asked Questions

  • NUCALA treats severe eosinophilic asthma in people who are 12 and older. It’s a prescription medicine your doctor adds to your other asthma medicines for maintenance, not for sudden breathing problems.

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  • If you and your doctor decide to add NUCALA to your severe asthma treatment, it can help you:

    • Prevent severe asthma attacks. Studies showed NUCALA reduced the number of severe asthma attacks by more than half.
    • Reduce the need for oral steroids. NUCALA is NOT a steroid. In fact, it helps reduce your use of steroids like prednisone while maintaining asthma control.
    • Reduce ER visits and/or hospitalizations and the disruptions they cause.

     

    Your results may vary.

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  • If your asthma is still uncontrolled even with your current high-dose daily medicines, you may not be treating one of the key causes of your kind of asthma: eosinophils. NUCALA is for severe eosinophilic asthma, so it’s designed to target eosinophils. If your doctor has given you a blood test and given you a severe eosinophilic asthma diagnosis, NUCALA may significantly reduce severe asthma attacks and your use of oral corticosteroids, like prednisone. Together, you and your doctor will decide if adding NUCALA to your other asthma medicines is right for you.

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  • No. NUCALA works with your current asthma medications to reduce your asthma attacks. Don’t make any changes in your severe asthma treatment without asking your asthma specialist.

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  • NUCALA can cause serious side effects, including:

    • allergic (hypersensitivity) reactions, including anaphylaxis. Serious allergic reactions can happen after you get your injection of NUCALA. Allergic reactions can sometimes happen hours or days after you get a dose of NUCALA. Tell your healthcare provider or get emergency help right away if you have any of the following symptoms of an allergic reaction:
      • swelling of your face, mouth, and tongue
      • breathing problems
      • fainting, dizziness, feeling light-headed (low blood pressure)
      • rash
      • hives
    • Herpes zoster infections that can cause shingles have happened in people who receive NUCALA.

    The most common side effects of NUCALA include: headache, injection site reactions (pain, redness, swelling, itching, or a burning feeling at the injection site), back pain, and weakness (fatigue).

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  • Before receiving NUCALA, tell your healthcare provider about all of your medical conditions, including if you:

    • are taking oral or inhaled corticosteroid medicines. Do not stop taking your other asthma medicines, including your corticosteroid medicines, unless instructed by your healthcare provider because this may cause other symptoms to come back.
    • have a parasitic (helminth) infection.
    • are pregnant or plan to become pregnant. It is not known if NUCALA may harm your unborn baby.
      • A pregnancy registry for women who receive NUCALA while pregnant collects information about the health of you and your baby. You can talk to your healthcare provider about how to take part in this registry or you can get more information and register by calling 1-877-311-8972 or visit www.mothertobaby.org/asthma.
    • are breastfeeding or plan to breastfeed. You and your healthcare provider should decide if you will use NUCALA and breastfeed. You should not do both without talking with your healthcare provider first.
    • are taking prescription and over-the-counter medicines, vitamins, and herbal supplements.

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  • Doctors consider your asthma severe if you take daily high-dose asthma medicines and have a history of severe asthma attacks (which are also called exacerbations). These attacks may have required steroids like prednisone, and you may have gone to the ER or been hospitalized to treat them. The more asthma attacks you’ve had, the more likely you are to have asthma attacks in the future. That’s why it’s important to talk to your asthma specialist about what may be causing your severe asthma, so you can work together to make it better controlled.

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  • Eosinophils [ee-uh-sin-uh-fils] are white blood cells that are a normal part of your immune system. When there are too many of them in your blood, they can worsen inflammation in your lungs. They are a key cause of severe eosinophilic asthma and can increase your risk for severe asthma attacks.

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