How NUCALA Works

NUCALA reduces the number of eosinophils (ee-uh-sin-uh-fils) in the blood. Eosinophils are a type of white blood cell that is a normal part of the body's immune system. Too many eosinophils can contribute to inflammation, which is a key component of EGPA. The mechanism of action of NUCALA is not fully understood.

 

How you will receive NUCALA

NUCALA for EGPA is given as 3 separate, 100-mg injections at the same time every 4 weeks. Tell your healthcare provider or get emergency help right away if you have any of the following symptoms of an allergic reaction: swelling of your face, mouth, and tongue; fainting, dizziness, feeling light-headed (low blood pressure); hives; breathing problems; or rash. Talk to your healthcare provider about any questions you may have.

  • If you receive your injections in your doctor’s office, you may be asked to stay in the office so your healthcare provider can monitor you for any allergic reactions, including anaphylaxis. Then you'll be able to leave, though sometimes serious allergic reactions can occur hours or days after.

  • If you take NUCALA at home, be sure to talk to your doctor about how to monitor for allergic reactions, including anaphylaxis, that can occur after a NUCALA injection, sometimes hours or days after you get your dose.

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Talk to your doctor to see if adding NUCALA for your EGPA is right for you.