How to Inject NUCALA at Home with CONFIDENCE

Your healthcare provider will give you information you need to inject properly and about monitoring for any allergic reactions. Sometimes, serious allergic reactions, including anaphylaxis, can occur hours or days later. Here you can find videos, instructions, and other useful information on how to use the NUCALA Autoinjector or prefilled syringe.   

Autoinjector Prefilled Syringe

IMPORTANT NOTICE FOR NUCALA AUTOINJECTOR USERS

  • The expected dose delivery time is up to 15 seconds. Some NUCALA Autoinjector devices may take longer.
  • Please carefully review the complete Instructions for Use (IFU) and view the video below before using the NUCALA Autoinjector.

 

Instructions for Injecting

 

Complete Instructions For Use
Quick Reference Guide

Storage Information
  • Store in the refrigerator between 36°F to 46°F (2°C to 8°C).
  • Keep in the original carton until time of use to protect from light.
  • Do not freeze. Do not shake. Keep away from heat.
  • If necessary, an unopened carton can be stored outside the refrigerator at up to 86°F (30°C) for up to 7 days.
  • Safely throw away the Autoinjector if it is left out of the refrigerator in the unopened carton for more than 7 days.
  • The Autoinjector must be used within 8 hours after you take it out of the carton. Safely throw it away if it is not used within 8 hours.
  • Safely throw away medicine that is out of date or no longer needed.

Keep NUCALA and all medicines out of the reach of children.

Warnings
  • Do not use any Autoinjector more than 1 time. Throw away the Autoinjector in an FDA-cleared sharps disposal container after your injection. 
  • Do not share the Autoinjector with other people. You may give other people a serious infection, or you may get a serious infection from them. 
  • Do not use the Autoinjector if it was dropped or looks damaged.

Autoinjector FAQs

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  • What should I expect when I receive my injections of NUCALA?

    You will receive NUCALA for EGPA as 3 separate injections given at the same time in an office visit or at home every 4 weeks. You, your caregiver, or your healthcare provider will inject NUCALA just under your skin (subcutaneously) into your thigh or abdomen. Your caregiver or your healthcare provider may also inject in your upper arm. It is recommended that the individual 100-mg injections be administered at least 5 cm (approximately 2 inches) apart if more than 1 injection is administered at the same site.

     

    If you receive your injection at your doctor’s office, you may be asked to stay in the office so your healthcare provider can monitor you for any allergic reactions, including anaphylaxis. Then you'll be able to leave, though sometimes serious allergic reactions can occur hours or days after you get your dose.

     

    If administering at home, be sure to talk to your doctor about how to monitor for allergic reactions, including anaphylaxis, that can occur after a NUCALA injection, sometimes hours or days after you get your dose.

     

    Tell your healthcare provider or get emergency help right away if you have any of the following symptoms of an allergic reaction: swelling of your face, mouth, and tongue; fainting, dizziness, feeling light-headed (low blood pressure); hives; breathing problems; or rash.

  • What happens if the medicine looks cloudy, the expiration date has passed, or the Autoinjector looks damaged?

    Do not use the Autoinjector. Contact GSK for more information at 1-888-825-5249.

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  • Can I change (rotate) the injection site for the Autoinjector?

    You may change (rotate) the site (thigh, abdomen, or upper arm) or move the Autoinjector as long as you have not started pressing down. When the yellow needle guard is pressed, your injection will start right away.

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  • Why do I need to inject within 5 minutes of removing the clear needle cap?

    This prevents the medicine from drying in the needle. It could affect how much medicine you get.

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  • What happens if I remove the Autoinjector before the 2nd click, the stopper has stopped moving, or the inspection window is not filled with the yellow indicator?

    If this happens, you may not have received your full dose. Contact GSK for more information at 1-888-825-5249.

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  • Who do I contact if I need help with my injection?

    Your healthcare provider will be able to help you with any more questions you might have.

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  • What do I do if I miss a dose?

    You or your caregiver should inject a dose of NUCALA as soon as you remember. Then, continue (resume) your injection on your regular dosing schedule. If you do not notice that you have missed a dose until it is time for your next scheduled dose, then just inject the next scheduled dose as planned. If you are not sure what to do, ask your doctor, pharmacist, or nurse.  

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  • How do I store my Autoinjector?

    Store in the refrigerator between 36°F to 46°F (2°C to 8°C). Keep in the original carton until time of use to protect from light. Do not freeze. Do not shake. Keep away from heat. If necessary, an unopened carton can be stored outside the refrigerator at up to 86°F (30°C) for up to 7 days. Safely throw away the prefilled Autoinjector if the unopened carton is left out of the refrigerator for more than 7 days.

     

    Autoinjectors must be used within 8 hours after you take them out of the carton. Safely throw away if not used within 8 hours.

     

    Keep NUCALA and all medicines out of the reach of children.

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  • What if I’m going on a trip or vacation and need to take my NUCALA with me?

    Store in the refrigerator between 36°F to 46°F (2°C to 8°C). Keep in the original carton until time of use to protect from light. Do not freeze. Do not shake. Keep away from heat. If necessary, an unopened carton can be stored outside the refrigerator at up to 86°F (30°C) for up to 7 days. Safely throw away the prefilled Autoinjector if the unopened carton is left out of the refrigerator for more than 7 days.

     

    Autoinjectors must be used within 8 hours after you take them out of the carton. Safely throw away if not used within 8 hours.

     

    Keep NUCALA and all medicines out of the reach of children.

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  • Can I reuse my Autoinjector?

    Do not use any Autoinjector more than once. Throw away the Autoinjector in an FDA-cleared sharps disposal container after your injection.

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  • Can I share my Autoinjector?

    Do not share the Autoinjector with other people. You may give other people a serious infection, or you may get a serious infection from them.

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    Yes, it was helpful.
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  • What should I do if my Autoinjector was dropped or looks damaged?

    Do not use the Autoinjector. Contact GSK at 1-888-825-5249.

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    Yes, it was helpful.
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  • The expiration date on my Autoinjector has passed. What should I do?

    Do not use the Autoinjector. Contact GSK at 1-888-825-5249.

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  • What should I do if a security seal on the carton is broken?

    Do not use the Autoinjector. Contact GSK at 1-888-825-5249.

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We're here for every step of your treatment journey.

Whether you're still thinking about starting NUCALA or have moved forward with NUCALA as a treatment option, MyNUCALA can support you along the way. MyNUCALA offers ways to help you track your progress, stay on your treatment plan, guide conversations with your doctor, and more.


The MyNUCALA Support Line is here to help answer questions about the self-injection process. Call 1-844-4-NUCALA (844-468-2252), Monday – Friday, 8 am to 8 pm ET.


If you have questions, contact your doctor or a healthcare provider.

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