How does NUCALA work?

NUCALA doesn’t stop short—it gets to a key source

NUCALA targets and reduces eosinophils, a key source of inflammation. Now, here are the facts:

Eosinophil graphic
Eosinophil graphic

NUCALA targets eosinophils

Eosinophils [ee-uh-sin-uh-fils] are white blood cells that are a normal part of the body’s immune system.

  • What this means for your nasal polyps: Too many eosinophils may lead to inflammation in your nasal passages. Because surgery doesn't eliminate this inflammation, the nasal polyps can come back.

NUCALA reduces eosinophils

NUCALA is not a steroid, like prednisone; it's a biologic. NUCALA is the first approved treatment that specifically targets and reduces eosinophils.*

  • What this means for your nasal polyps: Eosinophils are a key source of inflammation in nasal polyps. By targeting eosinophils, NUCALA may help reduce inflammation in your nasal passages.

*It is not fully understood how NUCALA works.


See what NUCALA can do.

Explore the benefits of NUCALA

At home. On your time.

Curious about taking your medication at home? Learn about a once-monthly,† at-home option.

Every 4 weeks.

What to expect during your first NUCALA treatment

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In the office

If you want to receive your NUCALA injections from your healthcare professional, you can have NUCALA administered in the office.

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At home on your time

NUCALA can also be taken at home with the Autoinjector. Your doctor will provide information on how to properly inject at home.

Talk to your doctor to see if adding NUCALA is right for you.