RESULTS WITH NUCALA

LET’S DIVE INTO RESULTS WITH NUCALA

NUCALA is a biologic, NOT a steroid. It's 3 injections you take every 4 weeks in addition to your current treatment plan to help reduce HES symptoms and prevent flares.

Here’s what NUCALA could do for you.

During an 8-month clinical study, people with HES who were treated with 300 mg of NUCALA saw:

PROTECTION from flares*†‡

72

%
of NUCALA patients did NOT have flares, compared to 44% of patients not taking NUCALA.

FEWER future flares‡

66

%
reduction in the number of future flares for patients taking NUCALA.

On average, NUCALA patients had 0.50 HES flares per year, compared to 1.46 HES flares per year for patients not taking NUCALA.

  • Results may vary.
  • *Based on limits of the analysis, results are descriptive and your experience may differ.
  • †28% of people taking NUCALA had one or more flares or withdrew from the study, compared to 56% of people not taking NUCALA.
  • ‡Flares were defined as worsening of signs/symptoms of HES or increase in blood eosinophil levels (on at least 2 exams) that required an increase in steroids and/or other HES therapy.

Patients on NUCALA also experienced:

Less fatigue§

Patients on NUCALA reported an improvement in fatigue.

Reduced symptoms

NUCALA helped reduce HES-related symptoms and flares.

  • Results may vary.
  • §In a study, patients reported an improvement in their worst level of fatigue compared to those not taking NUCALA.
Start the discussion

Have open conversations with your specialist.

Doing everything you can for your HES and it still doesn’t feel like enough? It’s time to have an open and honest conversation with your specialist. Here are some things to bring up:

  1. Talk about your flares. Tell your specialist about all the times your HES symptoms have gotten worse and ask if blood testing has shown an increase in blood eosinophil levels. This could mean a change in your HES therapy could help.
  2. Mention how you’re feeling. Let your specialist know about the times you’ve noticed your symptoms more. HES affects people differently, and symptoms can affect any part of the body.
  3. Discuss HES therapy. You have options when it comes to HES therapy. Ask your specialist about NUCALA and if it may be right for you.

Once a month.‖ At home. On YOUR time.

When it comes to your treatment, convenience is key. The NUCALA Autoinjector can be taken at home–just once a month. Want to learn more about using the Autoinjector?

‖Every 4 weeks

HOW TO INJECT NUCALA

Watch the science behind NUCALA

SEE NUCALA IN ACTION

Talk to your doctor to see if adding NUCALA is right for you.

Approved Use & Safety Info

Approved Use

Important Safety Information

Approved Use

NUCALA is a prescription medicine for the treatment of people 12 years of age and older with hypereosinophilic syndrome (HES) for 6 months or more.

Important Safety Information

Do not use NUCALA if you are allergic to mepolizumab or any of the ingredients in NUCALA.

NUCALA can cause serious side effects, including:

  • allergic (hypersensitivity) reactions, including anaphylaxis. Serious allergic reactions can happen after you get your NUCALA injection. Allergic reactions can sometimes happen hours or days after you get a dose of NUCALA. Tell your healthcare provider or get emergency help right away if you have any of the following symptoms of an allergic reaction:
    • swelling of your face, mouth, and tongue
    • breathing problems
    • fainting, dizziness, feeling lightheaded (low blood pressure)
    • rash
    • hives
  • herpes zoster infections that can cause shingles have happened in people who received NUCALA.

Before receiving NUCALA, tell your healthcare provider about all of your medical conditions, including if you:

  • are taking oral or inhaled corticosteroid medicines. Do not stop taking your other medicines, including your corticosteroid medicines, unless instructed by your healthcare provider because this may cause other symptoms to come back.
  • have a parasitic (helminth) infection.
  • are pregnant or plan to become pregnant. It is not known if NUCALA may harm your unborn baby.
  • are breastfeeding or plan to breastfeed. You and your healthcare provider should decide if you will use NUCALA and breastfeed. You should not do both without talking with your healthcare provider first.
  • are taking prescription and over-the-counter medicines, vitamins, and herbal supplements.

The most common side effects of NUCALA include: headache, injection site reactions (pain, redness, swelling, itching, or a burning feeling at the injection site), back pain, and tiredness (fatigue).

Please see full Prescribing Information for NUCALA.

You are encouraged to report negative side effects of prescription drugs to the FDA.
Visit www.fda.gov/medwatch or call 1-800-FDA-1088. You may also report negative side effects to GSK at gsk.public.reportum.com or 1-888-825-5249.
Visit GSK Help Center website

Explore the GSK Help Center website to find customer service support and contact information.

Contact Us
Visit GSK For You website

If you have questions about how to access your GSK medication or need cost information, visit gskforyou.com or call 1-866-GSK-FOR-U (1-866-475-3678).