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Ready for NUCALA?
Start here.

Your healthcare providers are your partners in managing your asthma. Their goal is to work with you to provide an asthma treatment plan that reduces your asthma attacks. Your asthma specialist, either a pulmonologist or an allergist, may prescribe NUCALA to help meet some of your goals.

Starting NUCALA is different from other asthma medicines.

Your doctor may start with a simple blood test to see if NUCALA is right for you. Read more about the test. After your doctor prescribes NUCALA:

It could come from a specialty pharmacy, not your local drugstore

Specialty Pharmacy

Your insurer may require that you get NUCALA from a particular specialty pharmacy. Here's a list of specialty pharmacies for NUCALA. A specialty pharmacy provides extra support for patients and focuses on certain conditions and medications. The pharmacy will verify your insurance benefit coverage, and it will help you get started.

The specialty pharmacy will ship NUCALA directly to your doctor's office, so the pharmacy may ask you for payment information to cover your co-payment.

If you have any concerns about paying for your medicine, find out how you can get help with your co-pay.

Remember to always return phone calls and messages from a specialty pharmacy or Gateway to NUCALA, even if the message doesn't mention NUCALA.


Your doctor could purchase it directly

Gateway to NUCALA

If your doctor is ordering NUCALA directly, or if you have completed your Services Request form, a representative from Gateway to NUCALA may call to review your insurance benefits summary and answer any questions you may have about your out-of-pocket costs. You may pay your out-of-pocket costs at your doctor's appointment.

If you have insurance questions or you want to enroll in the $0 Co-pay Program for NUCALA, you can call Gateway to NUCALA.

Gateway to NUCALA

Monday–Friday, 8AM to 8PM ET

1-844-4-NUCALA (1-844-468-2252) toll-free

Remember to always return phone calls and messages from a specialty pharmacy or Gateway to NUCALA, even if the message doesn't mention NUCALA.

You may receive a call from a specialty pharmacy or Gateway to NUCALA, and they may ask for your payment information. It's important to always promptly return phone calls and messages so there is no delay in starting your treatment. If a message is left they may not mention NUCALA in order to protect your privacy.

Once you get approval for NUCALA, here are the next steps:

  • Make an appointment, if you haven't already. You'll visit your asthma specialist's office, clinic, or hospital to get your first injection from a doctor or staff member. If you don't have an asthma specialist, find one near you here.
  • Expect important phone calls Be sure to return any calls from your specialty pharmacy or Gateway to NUCALA. Any delay in returning their calls could slow down the time to start NUCALA.
  • Receive your injection of NUCALA.NUCALA is injected just underneath your skin (subcutaneously), into your upper arm, thigh, or abdomen.
  • Prepare for your office visitOnce you receive your injection, you may be asked to stay in the office so your healthcare provider can monitor you for any allergic reactions, including anaphylaxis. Then you'll be able to leave, though sometimes serious allergic reactions can occur hours or days after.
  • Discuss your plan.Talk with your asthma specialist about your total asthma treatment plan and continue to take the other asthma medications prescribed for you.
  • Get answers to your questions. Find answers in our FAQs.
    Understand insurance coverage or $0 Co-pay Program at Gateway to NUCALA,
    Talk to an expert on NUCALA at our Nurse Support Line.

    We're here for you, all at one number: 1-844-4-NUCALA (1-844-468-2252) toll-free.
Important Safety Information

Do not use NUCALA if you are allergic to mepolizumab or any of the ingredients in NUCALA.

Important Safety Information

Do not use NUCALA if you are allergic to mepolizumab or any of the ingredients in NUCALA.

Do not use to treat sudden breathing problems.

NUCALA can cause serious side effects, including:

  • allergic (hypersensitivity) reactions, including anaphylaxis. Serious allergic reactions can happen after you get your injection of NUCALA. Allergic reactions can sometimes happen hours or days after you get a dose of NUCALA. Tell your healthcare provider or get emergency help right away if you have any of the following symptoms of an allergic reaction:
    • swelling of your face, mouth, and tongue
    • breathing problems
    • fainting, dizziness, feeling light-headed (low blood pressure)
    • rash
    • hives
  • Herpes zoster infections that can cause shingles have happened in people who received NUCALA.

Before receiving NUCALA, tell your healthcare provider about all of your medical conditions, including if you:

    • have not had chickenpox (varicella) or the chickenpox vaccine.
    • are taking oral or inhaled corticosteroid medicines. Do not stop taking your other asthma medicines, including your corticosteroid medicines, unless instructed by your healthcare provider because this may cause other symptoms to come back.
    • have a parasitic (helminth) infection.
    • are pregnant or plan to become pregnant. It is not known if NUCALA may harm your unborn baby.
      • A pregnancy registry for women who receive NUCALA while pregnant collects information about the health of you and your baby. You can talk to your healthcare provider about how to take part in this registry or you can get more information and register by calling 1-877-311-8972 or visit www.mothertobaby.org/asthma.
    • are breastfeeding or plan to breastfeed. You and your healthcare provider should decide if you will use NUCALA and breastfeed. You should not do both without talking with your healthcare provider first.
    • are taking prescription and over-the-counter medicines, vitamins, and herbal supplements.
  • The most common side effects of NUCALA include: headache, injection site reactions (pain, redness, swelling, itching, or a burning feeling at the injection site), back pain, and weakness (fatigue).

You are encouraged to report negative side effects of prescription drugs to the FDA.
Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.