RESULTS WITH NUCALA

IT’S TIME TO TALK RESULTS WITH NUCALA

NUCALA is the first FDA-approved treatment for EGPA (eosinophilic granulomatosis with polyangiitis). It’s 3 injections you take every 4 weeks in addition to your current treatment plan.

Let's dive into the results of the NUCALA clinical trial for EGPA

 

Patients who added NUCALA to their current EGPA medicines spent a significantly longer time in remission by the end of the 1-year study. And more patients had fewer relapses and a lower daily dose of oral steroids as well.

32% of NUCALA patients remained in complete remission at 36 and 48 weeks*

compared to 3% of patients not taking NUCALA.

50% fewer relapses a year†

NUCALA patients had 1.14 relapses/year compared to 2.27 relapses/year in patients not taking NUCALA.

59% of NUCALA patients lowered their dose of oral steroids‡§

compared to 34% of patients not taking NUCALA.‡

18% of NUCALA patients completely eliminated oral steroids in the last 4 weeks of treatment‡

compared to 3% of patients not taking NUCALA.‡

  • *"Complete remission" was defined as no active vasculitis and a prednisone or prednisolone dose less than or equal to 4 mg per day.
  • †"Relapse" was defined as worsening symptoms that required increased steroid dose, and/or increase in dose or start of immunosuppressants, and/or hospitalization.
  • ‡Based on the limits of the study, the results are descriptive, and your experience may or may not be the same.
  • §Reduced steroid dose to ≤7.5 mg in the last 4 weeks of treatment.

Watch the science behind NUCALA

SEE NUCALA IN ACTION

Get the conversation started

Being open and honest with your specialist is important. Use the Doctor Discussion Guide to help keep the conversation on track.

GET THE GUIDE

Once a month.II At home. On YOUR time.

When it comes to your treatment, convenience is key. The NUCALA Autoinjector can be taken at home–just once a month. Want to learn more about using the Autoinjector?

HOW TO INJECT NUCALA
  • ||Every 4 weeks.

Hear how NUCALA helps Ben live life with EGPA, on his terms.

VIEW HIS STORY

Talk to your doctor to see if adding NUCALA is right for you.

Approved Use & Safety Info

Approved Use

Important Safety Information

Approved Use

NUCALA is a prescription medicine for the treatment of adults with eosinophilic granulomatosis with polyangiitis (EGPA).

Important Safety Information

Do not use NUCALA if you are allergic to mepolizumab or any of the ingredients in NUCALA.

NUCALA can cause serious side effects, including:

  • allergic (hypersensitivity) reactions, including anaphylaxis. Serious allergic reactions can happen after you get your NUCALA injection. Allergic reactions can sometimes happen hours or days after you get a dose of NUCALA. Tell your healthcare provider or get emergency help right away if you have any of the following symptoms of an allergic reaction:
    • swelling of your face, mouth, and tongue
    • breathing problems
    • fainting, dizziness, feeling lightheaded (low blood pressure)
    • rash
    • hives
  • herpes zoster infections that can cause shingles have happened in people who received NUCALA.

Before receiving NUCALA, tell your healthcare provider about all of your medical conditions, including if you:

  • are taking oral or inhaled corticosteroid medicines. Do not stop taking your other medicines, including your corticosteroid medicines, unless instructed by your healthcare provider because this may cause other symptoms to come back.
  • have a parasitic (helminth) infection.
  • are pregnant or plan to become pregnant. It is not known if NUCALA may harm your unborn baby.
  • are breastfeeding or plan to breastfeed. You and your healthcare provider should decide if you will use NUCALA and breastfeed. You should not do both without talking with your healthcare provider first.
  • are taking prescription and over-the-counter medicines, vitamins, and herbal supplements.

The most common side effects of NUCALA include: headache, injection site reactions (pain, redness, swelling, itching, or a burning feeling at the injection site), back pain, and tiredness (fatigue).

Please see full Prescribing Information for NUCALA.

You are encouraged to report negative side effects of prescription drugs to the FDA.
Visit www.fda.gov/medwatch or call 1-800-FDA-1088. You may also report negative side effects to GSK at gsk.public.reportum.com or 1-888-825-5249.
Visit GSK Help Center website

Explore the GSK Help Center website to find customer service support and contact information.

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Visit GSK For You website

If you have questions about how to access your GSK medication or need cost information, visit gskforyou.com or call 1-866-GSK-FOR-U (1-866-475-3678).