UNDERSTANDING YOUR COPD 

MAYBE IT’S A DIFFERENT KIND OF COPD

If you are struggling with flare-ups even on maintenance inhaler treatments, it may mean that your symptoms are uncontrolled and that more could be going on with your COPD.

So, what are some signs of uncontrolled COPD?

More frequent use of a rescue inhaler

This could mean needing to use your rescue inhaler more than twice a week to manage some of your uncontrolled COPD symptoms such as: shortness of breath, wheezing, and chest tightness.

An oral steroid/antibiotic treatment

Are your flare-ups needing extra help lately? Just two or more flare-ups a year requiring an oral steroid could mean more is going on with your symptoms.

A hospital/ER visit

Do your flare-ups send you to the hospital or ER once a year or more? This is a sign that your COPD symptoms aren’t controlled, and you may need additional help.

Reduced activity

Are frequent flare-ups getting in the way? If your COPD symptoms are interfering with everyday tasks more often, it could mean your symptoms are not controlled.

If this sounds familiar, talk to your doctor about your current COPD treatments.

Fact: About 40%* of people with COPD have elevated levels of blood eosinophils, which increases the risk of flare-ups.

What are eosinophils?

*34-49%

What are eosinophils?

To understand the potential causes of your uncontrolled COPD symptoms, it's important to know what could be contributing to your inflammation.

One cause of your COPD inflammation could be eosinophils†—normal white blood cells that are part of your immune system. Too many eosinophils may lead to inflammation in your lungs, which can cause flare-ups.

Looking to learn more about the science of NUCALA?

HOW NUCALA WORKS
  • †It is not fully understood how NUCALA works.

Find out if there’s more to your COPD.

Here are some next steps you can take:

Schedule simple blood testing

Talk to your specialist about your symptoms and schedule simple blood testing, which can measure eosinophil levels.

Understand your diagnosis

If you receive a COPD diagnosis, learn more about your type of COPD and the different kinds of treatments available.

Ask about adding NUCALA

NUCALA is an add-on injection maintenance treatment for adults with eosinophilic COPD and is available in an easy-to-use Autoinjector.‡

‡Severe asthma patients rated the Autoinjector as easy-to-use after training. See full Instructions for Use

Need help finding a specialist?

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Watch the science behind NUCALA

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Talk to your doctor to see if adding NUCALA is right for you.

Approved Use & Safety Info

Approved Use

Important Safety Information

Approved Use

NUCALA is an add-on, prescription maintenance treatment of eosinophilic chronic obstructive pulmonary disease (COPD) in adults whose disease is not controlled. NUCALA is not used to treat sudden breathing problems.

Important Safety Information

Do not use NUCALA if you are allergic to mepolizumab or any of the ingredients in NUCALA.

Do not use to treat sudden breathing problems.

NUCALA can cause serious side effects, including:

  • allergic (hypersensitivity) reactions, including anaphylaxis. Serious allergic reactions can happen after you get your NUCALA injection. Allergic reactions can sometimes happen hours or days after you get a dose of NUCALA. Tell your healthcare provider or get emergency help right away if you have any of the following symptoms of an allergic reaction:
    • swelling of your face, mouth, and tongue
    • breathing problems
    • fainting, dizziness, feeling lightheaded (low blood pressure)
    • rash
    • hives
  • herpes zoster infections that can cause shingles have happened in people who received NUCALA.

Before receiving NUCALA, tell your healthcare provider about all of your medical conditions, including if you:

  • are taking oral or inhaled corticosteroid medicines. Do not stop taking your other medicines, including your corticosteroid medicines, unless instructed by your healthcare provider because this may cause other symptoms to come back.
  • have a parasitic (helminth) infection.
  • are pregnant or plan to become pregnant. It is not known if NUCALA may harm your unborn baby.
  • are breastfeeding or plan to breastfeed. You and your healthcare provider should decide if you will use NUCALA and breastfeed. You should not do both without talking with your healthcare provider first.
  • are taking prescription and over-the-counter medicines, vitamins, and herbal supplements.

The most common side effects of NUCALA include: headache, injection site reactions (pain, redness, swelling, itching, or a burning feeling at the injection site), back pain, and tiredness (fatigue). Diarrhea and cough have been reported with COPD.

Please see full Prescribing Information for NUCALA.

You are encouraged to report negative side effects of prescription drugs to the FDA.
Visit www.fda.gov/medwatch or call 1-800-FDA-1088. You may also report negative side effects to GSK at gsk.public.reportum.com or 1-888-825-5249.
Visit GSK Help Center website

Explore the GSK Help Center website to find customer service support and contact information.

Contact Us
Together with NUCALA logo

If you have questions about how to access or pay for your GSK medication, visit togetherwithnucala.com or call 1-844-Call-TwGSK (1-844-475-3678).