HOW DOES NUCALA WORK?

NUCALA is not an inhaler or a steroid—it's a biologic! NUCALA works by targeting inflammation and reducing eosinophils.* Eosinophils are normal white blood cells that are part of your immune system. But too many of them may lead to inflammation in your lungs, which can cause flare-ups.

  • Results may vary.
  • *It is not fully understood how NUCALA works.

Watch the science behind NUCALA.

Key take-aways:

NUCALA targets inflammation

Inflammation triggering your COPD flare-ups may be caused by eosinophils—normal white blood cells in the body.*

What this means for your COPD: In some cases, higher levels of eosinophils could be contributing to inflammation in the lungs. That inflammation can cause flare-ups or exacerbate COPD symptoms.

NUCALA could help reduce eosinophils

NUCALA is not a steroid like prednisone. It targets inflammation and reduces eosinophils in your blood.*

What this means for your COPD: NUCALA may be able to reduce COPD inflammation, which can mean less flare-ups for you. Results may vary.

*It is not fully understood how NUCALA works.

Simple blood testing can measure the number of eosinophils in your blood

Based on your test results, along with your medical history and other information, your doctor may add NUCALA to your treatment.

WHAT IS A BIOLOGIC?

Biologics are treatments derived from natural sources and are able to help target certain immune cells, such as eosinophils in COPD, which can contribute to inflammation.

When it comes to COPD treatment, convenience is key.

With the easy-to-use† Autoinjector, you can take NUCALA either right at home or at your specialist's office. Want to know more?

ABOUT THE AUTOINJECTOR

†Severe asthma patients rated the Autoinjector as easy-to-use after training. See full Instructions for Use

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Talk to your doctor to see if adding NUCALA is right for you.

Approved Use & Safety Info

Approved Use

Important Safety Information

Approved Use

NUCALA is an add-on, prescription maintenance treatment of eosinophilic chronic obstructive pulmonary disease (COPD) in adults whose disease is not controlled. NUCALA is not used to treat sudden breathing problems.

Important Safety Information

Do not use NUCALA if you are allergic to mepolizumab or any of the ingredients in NUCALA.

Do not use to treat sudden breathing problems.

NUCALA can cause serious side effects, including:

  • allergic (hypersensitivity) reactions, including anaphylaxis. Serious allergic reactions can happen after you get your NUCALA injection. Allergic reactions can sometimes happen hours or days after you get a dose of NUCALA. Tell your healthcare provider or get emergency help right away if you have any of the following symptoms of an allergic reaction:
    • swelling of your face, mouth, and tongue
    • breathing problems
    • fainting, dizziness, feeling lightheaded (low blood pressure)
    • rash
    • hives
  • herpes zoster infections that can cause shingles have happened in people who received NUCALA.

Before receiving NUCALA, tell your healthcare provider about all of your medical conditions, including if you:

  • are taking oral or inhaled corticosteroid medicines. Do not stop taking your other medicines, including your corticosteroid medicines, unless instructed by your healthcare provider because this may cause other symptoms to come back.
  • have a parasitic (helminth) infection.
  • are pregnant or plan to become pregnant. It is not known if NUCALA may harm your unborn baby.
  • are breastfeeding or plan to breastfeed. You and your healthcare provider should decide if you will use NUCALA and breastfeed. You should not do both without talking with your healthcare provider first.
  • are taking prescription and over-the-counter medicines, vitamins, and herbal supplements.

The most common side effects of NUCALA include: headache, injection site reactions (pain, redness, swelling, itching, or a burning feeling at the injection site), back pain, and tiredness (fatigue). Diarrhea and cough have been reported with COPD.

Please see full Prescribing Information for NUCALA.

You are encouraged to report negative side effects of prescription drugs to the FDA.
Visit www.fda.gov/medwatch or call 1-800-FDA-1088. You may also report negative side effects to GSK at gsk.public.reportum.com or 1-888-825-5249.
Visit GSK Help Center website

Explore the GSK Help Center website to find customer service support and contact information.

Contact Us
Together with NUCALA logo

If you have questions about how to access or pay for your GSK medication, visit togetherwithnucala.com or call 1-844-Call-TwGSK (1-844-475-3678).