Once-monthly NUCALA now approved for COPD

NUCALA is an add-on, prescription maintenance treatment of eosinophilic chronic obstructive pulmonary disease (COPD) in adults whose 
disease is not controlled. NUCALA is not used to treat sudden breathing problems.

*Every 4 weeks.

What could adding NUCALA mean for you?

LESS flare-ups

Results may vary.

LESS hospitalizations due to flare-ups†

Results may vary.

†Based on the limits of the study, this result is descriptive.

LESS total doses per year vs other COPD biologic‡

No comparative efficacy or safety conclusions can be drawn from this information.

‡Every 4 weeks vs every other week.

So what's a flare-up?

Flare-ups (or exacerbations):

When symptoms get so bad you may need additional treatments—like antibiotics or steroids—or even a trip to the hospital. Just one flare-up can decrease your lung function, so finding the right treatment for your COPD is important.

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Key source - eosinophils

Maybe it’s a different kind of COPD

If you or a loved one are struggling with COPD flare-ups, even on maintenance inhaler treatment, this could mean that your COPD symptoms are uncontrolled. This may be due to something that’s naturally happening inside the body.

Eosinophils (ee-uh-sin-uh-fils), which are normal white blood cells, are a key source of inflammation in the lungs that could be contributing to flare-ups. For those who have COPD with high levels of blood eosinophils, it may be eosinophilic COPD.

EOSINOPHILIC COPD = A DIFFERENT KIND OF COPD

Fact: About 40%§ of people with COPD have elevated levels of blood eosinophils

§34-49%

NUCALA is a different kind of COPD treatment

It’s not an inhaler or a steroid. NUCALA is the first and only once-monthly* biologic for eosinophilic COPD. It works by targeting and reducing blood eosinophils, which may help reduce airway inflammation.‖ Less inflammation could mean fewer flare-ups.

What's a biologic? Biologics are treatments derived from natural sources and are used to help target key causes of many conditions, like eosinophils in COPD.

  • ‖It is not fully understood how NUCALA works.

Once a month.* At home. On YOUR time.

When it comes to your COPD treatment, convenience is key. You can take the NUCALA Autoinjector at home—just once a month. Want to see how easy the Autoinjector could be for you to use?

HOW TO INJECT NUCALA
  • *Every 4 weeks.
  • Severe asthma patients rated the Autoinjector as easy-to-use after training. See full Instructions for Use.

At home not for you? No problem.

You can get your NUCALA injections at your specialist’s office every 4 weeks. Just know, it’s important to monitor for serious allergic reactions after injection, either in your specialist’s office or at home. Sometimes serious allergic reactions, including anaphylaxis, can happen hours or days after you get your NUCALA injection.

What's next?

Find out if NUCALA is right for your kind of COPD.

Ask your specialist about simple blood testing to measure eosinophil levels.

Want to learn more about NUCALA?

Check out the brochure for more info and tips on talking to your specialist.

Download brochure

Questions about NUCALA costs?

When it comes to paying for NUCALA, there may be savings available to you.

Check your eligibility

Need help understanding insurance coverage?

Get the facts you need to make informed decisions based on your circumstances. 

Explore insurance info

Talk to your doctor to see if adding NUCALA is right for you.

Approved Use & Safety Info

Approved Use

Important Safety Information

Approved Use

NUCALA is an add-on, prescription maintenance treatment of eosinophilic chronic obstructive pulmonary disease (COPD) in adults whose disease is not controlled. NUCALA is not used to treat sudden breathing problems.

Important Safety Information

Do not use NUCALA if you are allergic to mepolizumab or any of the ingredients in NUCALA.

Do not use to treat sudden breathing problems.

NUCALA can cause serious side effects, including:

  • allergic (hypersensitivity) reactions, including anaphylaxis. Serious allergic reactions can happen after you get your NUCALA injection. Allergic reactions can sometimes happen hours or days after you get a dose of NUCALA. Tell your healthcare provider or get emergency help right away if you have any of the following symptoms of an allergic reaction:
    • swelling of your face, mouth, and tongue
    • breathing problems
    • fainting, dizziness, feeling lightheaded (low blood pressure)
    • rash
    • hives
  • herpes zoster infections that can cause shingles have happened in people who received NUCALA.

Before receiving NUCALA, tell your healthcare provider about all of your medical conditions, including if you:

  • are taking oral or inhaled corticosteroid medicines. Do not stop taking your other medicines, including your corticosteroid medicines, unless instructed by your healthcare provider because this may cause other symptoms to come back.
  • have a parasitic (helminth) infection.
  • are pregnant or plan to become pregnant. It is not known if NUCALA may harm your unborn baby.
  • are breastfeeding or plan to breastfeed. You and your healthcare provider should decide if you will use NUCALA and breastfeed. You should not do both without talking with your healthcare provider first.
  • are taking prescription and over-the-counter medicines, vitamins, and herbal supplements.

The most common side effects of NUCALA include: headache, injection site reactions (pain, redness, swelling, itching, or a burning feeling at the injection site), back pain, and tiredness (fatigue). Diarrhea and cough have been reported with COPD.

Please see full Prescribing Information for NUCALA.

You are encouraged to report negative side effects of prescription drugs to the FDA.
Visit www.fda.gov/medwatch or call 1-800-FDA-1088. You may also report negative side effects to GSK at gsk.public.reportum.com or 1-888-825-5249.
Visit GSK Help Center website

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If you have questions about how to access your GSK medication or need cost information, visit gskforyou.com or call 1-866-GSK-FOR-U (1-866-475-3678).