UNDERSTANDING NASAL POLYPS

FIRST THINGS FIRST—WHAT ARE NASAL POLYPS?

Nasal polyps are growths that form in your nasal passages or sinuses. When they’re linked to chronic rhinosinusitis, it’s called chronic rhinosinusitis with nasal polyps (CRSwNP). They can cause uncomfortable symptoms and sometimes require surgery to remove them. The good news? Surgery is not your only option. 

Fact: nasal polyps can grow back even after surgery

 

And that means your symptoms can come back with them. As you know, recurring nasal polyps can lead to:

Post-nasal drip & frequent nose blowing

Nasal congestion & loss of smell

Facial pain

Key source: eosinophils

NUCALA gets to a key source—eosinophils.

It’s not you. It’s biology. Having nasal polyps means there’s inflammation in your nasal passages that can be caused by elevated levels of eosinophils—normal white blood cells in your body. Because surgery doesn’t eliminate this inflammation, nasal polyps can grow back.

 

NUCALA is a non-surgical treatment that targets and reduces eosinophils,* a key source of inflammation causing your symptoms.

 

Interested in knowing more? Let’s get to it.

HOW NUCALA WORKS

* It is not fully understood how NUCALA works.

Next step: advocating for yourself.

 

When your nasal polyp symptoms are all you can think about, it’s time to ask your doctor about NUCALA—a non-surgical option.

Curious what else NUCALA can do?

Take a look at the data we’ve gathered to help you understand NUCALA better.

RESULTS WITH NUCALA

Talk to your doctor to see if adding NUCALA is right for you.

Approved Use & Safety Info

Approved Use

Important Safety Information

Approved Use

NUCALA is a prescription medicine for add-on maintenance treatment of chronic rhinosinusitis with nasal polyps (CRSwNP) in adults whose disease is not controlled with nasal corticosteroids.

Important Safety Information

Do not use NUCALA if you are allergic to mepolizumab or any of the ingredients in NUCALA.

NUCALA can cause serious side effects, including:

  • allergic (hypersensitivity) reactions, including anaphylaxis. Serious allergic reactions can happen after you get your NUCALA injection. Allergic reactions can sometimes happen hours or days after you get a dose of NUCALA. Tell your healthcare provider or get emergency help right away if you have any of the following symptoms of an allergic reaction:
    • swelling of your face, mouth, and tongue
    • breathing problems
    • fainting, dizziness, feeling lightheaded (low blood pressure)
    • rash
    • hives
  • herpes zoster infections that can cause shingles have happened in people who received NUCALA.

Before receiving NUCALA, tell your healthcare provider about all of your medical conditions, including if you:

  • are taking oral or inhaled corticosteroid medicines. Do not stop taking your corticosteroid medicines, unless instructed by your healthcare provider because this may cause other symptoms to come back.
  • have a parasitic (helminth) infection.
  • are pregnant or plan to become pregnant. It is not known if NUCALA may harm your unborn baby.
  • are breastfeeding or plan to breastfeed. You and your healthcare provider should decide if you will use NUCALA and breastfeed. You should not do both without talking with your healthcare provider first.
  • are taking prescription and over-the-counter medicines, vitamins, and herbal supplements.

The most common side effects of NUCALA include: headache, injection site reactions (pain, redness, swelling, itching, or a burning feeling at the injection site), back pain, tiredness (fatigue). Mouth/throat pain and joint pain have been reported with CRSwNP.

Please see full Prescribing Information for NUCALA.

You are encouraged to report negative side effects of prescription drugs to the FDA.
Visit www.fda.gov/medwatch or call 1-800-FDA-1088. You may also report negative side effects to GSK at gsk.public.reportum.com or 1-888-825-5249.
Visit GSK Help Center website

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If you have questions about how to access your GSK medication or need cost information, visit gskforyou.com or call 1-866-GSK-FOR-U (1-866-475-3678).