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Here are some important questions to ask your asthma specialist about NUCALA.

Turn to your asthma specialist for answers.

If you have severe asthma, an asthma specialist, like a pulmonologist or an allergist, is the right expert to help you manage your type of asthma. If you don't have an asthma specialist, find one near you here. Read more about how your doctor will determine if your asthma is severe.

It's important to tell your doctor everything you're doing to manage your asthma, and if asthma is interfering with your daily activities. Be prepared to help your asthma specialist understand if your asthma remains uncontrolled.

At your next visit, tell your doctor:

  • How many asthma attacks you've had in the past 12 months
  • How many times you've taken steroids (prednisone) for your asthma in the past 12 months
  • How your asthma interferes with your daily activities
  • About your current asthma medications and how often you take them

NUCALA is an injection you receive every 4 weeks. It works with your current asthma medicines to help you gain asthma control while cutting down on the use of steroids like prednisone. Your results may vary.

Interested in NUCALA?
Questions to ask your asthma specialist:

  • How is NUCALA different from my other asthma medications?
  • Will taking NUCALA change the dose of or how often I take my other asthma medications?
  • What are eosinophils? And how do they affect my asthma?
  • What can I expect when I start taking NUCALA?
  • What happens if I miss an injection appointment?
  • Should I stop taking NUCALA if my symptoms get better?

Get additional help with getting started on NUCALA or go to FAQs.

Print your Doctor Discussion Guide
Important Safety Information

Do not use NUCALA if you are allergic to mepolizumab or any of the ingredients in NUCALA.

Important Safety Information

Do not use NUCALA if you are allergic to mepolizumab or any of the ingredients in NUCALA.

Do not use to treat sudden breathing problems.

NUCALA can cause serious side effects, including:

  • allergic (hypersensitivity) reactions, including anaphylaxis. Serious allergic reactions can happen after you get your injection of NUCALA. Allergic reactions can sometimes happen hours or days after you get a dose of NUCALA. Tell your healthcare provider or get emergency help right away if you have any of the following symptoms of an allergic reaction:
    • swelling of your face, mouth, and tongue
    • breathing problems
    • fainting, dizziness, feeling light-headed (low blood pressure)
    • rash
    • hives
  • Herpes zoster infections that can cause shingles have happened in people who received NUCALA.

Before receiving NUCALA, tell your healthcare provider about all of your medical conditions, including if you:

    • have not had chickenpox (varicella) or the chickenpox vaccine.
    • are taking oral or inhaled corticosteroid medicines. Do not stop taking your other asthma medicines, including your corticosteroid medicines, unless instructed by your healthcare provider because this may cause other symptoms to come back.
    • have a parasitic (helminth) infection.
    • are pregnant or plan to become pregnant. It is not known if NUCALA may harm your unborn baby.
      • A pregnancy registry for women who receive NUCALA while pregnant collects information about the health of you and your baby. You can talk to your healthcare provider about how to take part in this registry or you can get more information and register by calling 1-877-311-8972 or visit www.mothertobaby.org/asthma.
    • are breastfeeding or plan to breastfeed. You and your healthcare provider should decide if you will use NUCALA and breastfeed. You should not do both without talking with your healthcare provider first.
    • are taking prescription and over-the-counter medicines, vitamins, and herbal supplements.
  • The most common side effects of NUCALA include: headache, injection site reactions (pain, redness, swelling, itching, or a burning feeling at the injection site), back pain, and weakness (fatigue).

You are encouraged to report negative side effects of prescription drugs to the FDA.
Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.