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Prevent severe asthma attacks with NUCALA.

What makes NUCALA different from other asthma medications you take?

  • It's not a steroid or an inhaler.
  • It is an injection you get in your doctor's office once every four weeks.
  • It reduces the number of eosinophils [ee-uh-sin-uh-fils] in your blood to help reduce airway inflammation.*
  • NUCALA treats a source of severe asthma, not just the symptoms.

If you still have asthma symptoms even though you take your daily asthma treatment, you may need to add NUCALA. NUCALA works with your current asthma medicines to decrease airway inflammation that can trigger severe asthma attacks.

Is it time to ask your doctor about adding NUCALA?

*The mechanism of action of NUCALA is not fully understood.

Add NUCALA to your asthma medications to:

  • Prevent severe asthma attacks. Studies have proven that NUCALA significantly reduced the occurrence of severe asthma attacks by more than half.
  • Reduce ER visits and/or hospitalizations and the disruptions they cause.
  • Reduce the use of oral steroids. NUCALA is NOT a steroid, and when added to your asthma medication, it helps to reduce your use of steroids like prednisone.

    Your results may vary.

Studies also showed that NUCALA helped:

  • Improve asthma control and reduce symptoms.
  • Improve daily life. In a study, people with severe asthma stated they had a better health-related quality of life after taking NUCALA.

Based on the limits of the study, the results are descriptive and your experience may or may not be the same.

I found out I needed more to treat my type of asthma.
I found out I needed more to treat my type of asthma.
Important Safety Information

Do not use NUCALA if you are allergic to mepolizumab or any of the ingredients in NUCALA.

Important Safety Information

Do not use NUCALA if you are allergic to mepolizumab or any of the ingredients in NUCALA.

Do not use to treat sudden breathing problems.

NUCALA can cause serious side effects, including:

  • allergic (hypersensitivity) reactions, including anaphylaxis. Serious allergic reactions can happen after you get your injection of NUCALA. Allergic reactions can sometimes happen hours or days after you get a dose of NUCALA. Tell your healthcare provider or get emergency help right away if you have any of the following symptoms of an allergic reaction:
    • swelling of your face, mouth, and tongue
    • breathing problems
    • fainting, dizziness, feeling light-headed (low blood pressure)
    • rash
    • hives
  • Herpes zoster infections that can cause shingles have happened in people who received NUCALA.

Before receiving NUCALA, tell your healthcare provider about all of your medical conditions, including if you:

    • have not had chickenpox (varicella) or the chickenpox vaccine.
    • are taking oral or inhaled corticosteroid medicines. Do not stop taking your other asthma medicines, including your corticosteroid medicines, unless instructed by your healthcare provider because this may cause other symptoms to come back.
    • have a parasitic (helminth) infection.
    • are pregnant or plan to become pregnant. It is not known if NUCALA may harm your unborn baby.
      • A pregnancy registry for women who receive NUCALA while pregnant collects information about the health of you and your baby. You can talk to your healthcare provider about how to take part in this registry or you can get more information and register by calling 1-877-311-8972 or visit www.mothertobaby.org/asthma.
    • are breastfeeding or plan to breastfeed. You and your healthcare provider should decide if you will use NUCALA and breastfeed. You should not do both without talking with your healthcare provider first.
    • are taking prescription and over-the-counter medicines, vitamins, and herbal supplements.
  • The most common side effects of NUCALA include: headache, injection site reactions (pain, redness, swelling, itching, or a burning feeling at the injection site), back pain, and weakness (fatigue).

You are encouraged to report negative side effects of prescription drugs to the FDA.
Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.